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Nu Skin Scientists Present ageLOC Research at
International Conference on Mitochondria
Targeting Age-Related Genes with Nutritional
Strategies Improves Vitality
Published: Friday, 3 Dec 2010 | 8:30 AM ET
PROVO, Utah, Dec. 3, 2010 /PRNewswire via COMTEX/ — Nu Skin (NYSE: NUS) scientists
presented research findings on how mental and physical vitality is improved through nutritional
strategies that influence mitochondrial-related genetic expression. Two oral presentations were made
at the First World Congress on Targeting Mitochondria: Strategies, Innovation and Clinical
Applications in Berlin.
Through Nu Skin’s innovative ageLOC science we have successfully identified groups of genes and
multiple genetic pathways that play a role in the complex process of aging, said Joe Chang, Ph.D., Nu
Skin chief scientific officer and executive vice president of product development. Nu Skin’s most
recent research focuses on improving physical, mental and sexual vitality that declines through the
normal aging process. Unlike others who employ single gene approaches, with our research partners
we identified multiple genes that affect mitochondrial function and also validate natural ingredients
that positively affect the expression of those genes, thereby impacting overall energy and vitality. We
believe that research focused on multiple genes shown to affect the normal aging process is the
optimal approach to develop effective anti-aging products.
Improved Mental Vitality
At the First World Congress on Targeting Mitochondria, Nu Skin senior scientist Scott Ferguson
presented Targeting Age-Related Gene Expression Improves Mental and Physical Vitality and
highlighted studies with a patent-pending blend of ingredients to improve physical, mental and sexual
vitality. This blend was shown to reset mitochondrial-related gene expression to a more youthful state.
In a pilot study on mental acuity, the blend significantly improved multiple attributes of cognitive
function in men and women aged 28-50 over those taking a placebo.
Improved Physical Vitality
In a second study, Ferguson presented evidence that revealed improved energy levels in mice
supplemented with the same proprietary ingredient blend as the mental acuity study. After seven
weeks physical endurance was improved in the supplemented group as compared to a placebo group.
Furthermore, the scientists reported that, relative to the placebo group, the supplemented group
retained more muscle glycogen and had reduced lactic acid buildup during exercise.
Identifying Ingredients to Combat Aging
Steve Wood, Ph.D., R.D., director of global research for Nu Skin’s nutritional brand, Pharmanex,
presented, A Nutritional Strategy to Oppose the Genetic Expression of Aging and Loss of Vitality. The
research described an algorithm Nu Skin’s partner LifeGen Technologies uses to identify genetic
supermarkers of aging. Natural ingredients were then screened for their impact on the genetic
expression of those supermarkers. This study further suggests that the aging process is influenced by
the expression of several genes and that a single gene change cannot account for the entire range of
age-related disorders.
About Targeting Mitochondria
2010 The First World Congress on Targeting Mitochondria 2010 was held Nov. 18-19 in Berlin and
attended by scientists from 26 countries. The event was sponsored by several organizations including
the International Society of Antioxidants in Nutrition and Health (ISANH), the French Society of
Antioxidants (SFA) and the Japanese Society of Antioxidants (JSA). As many believe the future of
medicine and human health will probably come through mitochondria, the conference was designed to
draw attention to controversies and provide answers and perspectives of mitochondrial function as a
target, as well as highlight applications and potential strategies in the prevention and treatment of
many chronic conditions.
About Nu Skin Enterprises
Nu Skin Enterprises, Inc. demonstrates its tradition of innovation through its comprehensive anti-aging
product portfolio, independent business opportunity and corporate social responsibility initiatives. The
company’s scientific leadership in both skin care and nutrition has established Nu Skin as a premier
anti-aging company, evidenced in its unique ageLOC(TM) science that addresses aging at its source.
The company’s anti-aging products feature the new ageLOC suite of products including the ageLOC
Transformation daily skin care system, ageLOC Future Serum and the ageLOC Edition Galvanic
Spa(R) System II, as well as the ageLOC Vitality nutritional supplement. A global direct selling
company, Nu Skin operates in 53 markets worldwide and has more than 785,000 independent distributors.